Investigation of Possible Role of Chlamydia in Pseudoexfoliation Syndrome

Background: Pseudoexfoliation syndrome (PES) is a systemic disease characterized by the aggregation of fibrillar extracellular material in intraocular and extraocular tissues with unknown etiology. Clarifying etiopathogenesis PES would be important for public health. Objectives: We aimed to investigate possible role Chlamydia etiology PES. Methods: This cross-sectional study was carried out ophthalmology clinic tertiary hospital. The included two groups, including patient group (PES patients nuclear cataracts) control (patients cataracts). Patients other ophthalmic problems diseases were excluded. Blood samples conjunctival swabs taken from 49 42 controls used study. Anti-Chlamydia trachomatis IgG IgM, anti-C. pneumoniae Interleukin (IL)-6, IL-20 studied serum samples. PCR performed swab sequence analysis PCR-positive performed. Results: According results study, there no statistically significant difference between groups terms trachmatis IgG, IL-6, results. There levels. DNA sequencing all products found compatible C. pneumoniae. Conclusions: It seems that might have an development However, further studies larger are needed clarify these